C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 221/18 (2006.01) A61K 31/435 (2006.01) A61K 31/473 (2006.01) C07D 491/04 (2006.01)
Patent
CA 2266321
The present invention provides compounds of formula (I) wherein R1-R7, W, X, Y, and Z have any of the values defined in the specification, and pharmaceutically acceptable salt thereof, that are useful as anticancer agents. Also disclosed are pharmaceutical compositions comprising one or more compounds of formula (I), processes for preparing compounds of formula (I), and intermediates useful for preparing compounds of formula (I).
La présente invention concerne des composés de la formule (I) dans laquelle R¿1?-R¿7?, W, X, Y, et Z présentent n'importe laquelle des valeurs définies dans la spécification, et un sel de ces composés acceptable du point de vue pharmaceutique, ces composés s'utilisant comme agents anticancéreux. L'invention concerne également des compositions pharmaceutiques comprenant un ou plusieurs composés de la formule (I), des procédés de préparation de composés de la formule (I), et des produits intermédiaires utiles dans la préparation de composés de la formule (I).
Lavoie Edmond J.
Liu Leroy Fong
Makhey Darshan B.
Lavoie Edmond J.
Liu Leroy Fong
Makhey Darshan B.
Rutgers The State University Of New Jersey
Smart & Biggar
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