C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/00 (2006.01)
Patent
CA 2636109
Various system and method embodiments of the present invention are directed to separating target molecules from complex solutions by affinity column chromatography using organic-solvent-containing eluants. In one embodiment of the present invention, an eluant containing an organic-solvent is used, at a first pH, to remove non-target solutes and suspended entities from an affinity chromatography column. The pH of the eluant is then changed to a second pH, and the organic- solvent-containing eluant is used to elute target molecules from the affinity column chromatography.
La présente invention concerne divers modes de réalisation de systèmes et de procédés destinés à séparer des molécules cibles de solutions complexes par chromatographie d~affinité sur colonne à l~aide d~éluants contenant des solvants organiques. Selon un mode de réalisation de la présente invention, un éluant contenant un solvant organique est utilisé, à un premier pH, pour retirer des solutés non-cibles et des entités en suspension d~une colonne de chromatographie d~affinité. Le pH de l~éluant est ensuite changé en un second pH et l~éluant contenant un solvant organique est utilisé pour éluer les molécules cibles de la chromatographie d~affinité sur colonne.
Amgen Inc.
Gowling Lafleur Henderson Llp
LandOfFree
Methods and systems for isolating target molecules from... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods and systems for isolating target molecules from..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods and systems for isolating target molecules from... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1399248