Recombinant epstein-barr viral capsid antigen useful in...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/38 (2006.01) C07K 14/05 (2006.01) G01N 33/543 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2150691

Recombinant EBV-gp125 protein is made in a baculovirus expression system in sufficient quantity and purity to enable its use in assays such as ELISAs for quantitative detection of EBV VCA-IgG and VCA-IgM antibodies. The recombinant gp125 protein is similar in size to EBV-gp125 viral capsid antigen isolated from EBV-infected human cell lines, and has similar sensitivity and specificity in immunological assays for VCA-Ig antibodies.

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