Means and methods for monitoring protease inhibitor...

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/18 (2006.01) C12Q 1/68 (2006.01) C12Q 1/70 (2006.01) G01N 33/569 (2006.01) G01N 33/573 (2006.01)

Patent

CA 2422815

This invention relates to antiviral drug susceptibility and resistance tests to be used in identifying effective drug regimens for the treatment of human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS), particularly treatment regimens including a protease inhibitor. The invention further relates to the means and methods of monitoring the clinical progression of HIV infection and its response to antiretroviral therapy using phenotypic or genotypic susceptibility assays.

L'invention porte sur des essais de susceptibilité et se résistance à des médicaments antiviraux servant à identifier des posologies efficaces pour le traitement d'infections par le VIH, et du SIDA, dont en particulier des posologies incluant un inhibiteur de protéase. L'invention porte également sur des moyens et procédés de suivi de la progression de l'infection par le VIH, et de sa réponse à une thérapie antivirale dans le cadre d'essais de susceptibilité aux phénotypes et génotypes.

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