Polymorph salt of a pyridazinone derivative for the...

C - Chemistry – Metallurgy – 07 – D

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C07D 237/22 (2006.01) A61K 31/50 (2006.01)

Patent

CA 2454774

The invention relates to the new crystalline form I 5-chloro-4-[3-[N-[2-(3,4- dimethoxy-phenyl)-ethyl]-N-methylamino]-propylamino]-3-[2H]-pyridazinone fumarate, a process for the preparation thereof, pharmaceutical compositions containing the same and the use of said new polymorph for the treatment of arrhythmia.

Cette invention concerne un nouveau 5-chloro-4-[3-[N-[2-(3,4-diméthoxy-phényl)-éthyl]-N-méthylamino]-propylamino]-3-[2H]-pyridazinone fumarate de forme cristalline I, son procédé de préparation, des compositions pharmaceutiques renfermant ce composé ainsi que l'utilisation de ce nouveau polymorphe pour le traitement de l'arythmie. (I)

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