C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 513/14 (2006.01) A61K 31/395 (2006.01) C07D 498/14 (2006.01) C07D 519/00 (2006.01)
Patent
CA 2117062
- 40 - A b s t r a c t The present invention concerns thiazolo-[2,3-a]pyrrole and oxazolo-[1,2-a]pyrrole derivatives of formula I Image (I), in which HET represents a heterocyclic ring with 3-7 ring atoms which can be substituted by one, two or three residues R1 which can be the same or different, Y represents an oxygen or sulphur atom, or a SO or SO2 group, X can be an oxygen or sulphur atom, R denotes an aliphatic residue with 1-9 C-atoms which can be substituted by phenyl or denotes a phenyl ring or a carbocyclic ring with 7-15 C atoms or a heterocyclic ring system each having 5 or 6 ring atoms, in which the aforementioned phenyl rings, carbocyclic rings or heterocyclic ring system can be substituted once or several times, if desired, and R1 - R5 denote - 41 - hydrogen or an aliphatic residue, as well as their tautomers, enantiomers, diastereomers and physiologically tolerated salts. In addition the invention concerns pharmaceutical agents which contain compounds of formula I.
Leinert Herbert
Mertens Alfred
Zilch Harald
Roche Diagnostics Gmbh
Swabey Ogilvy Renault
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