A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/00 (2006.01) A61K 39/205 (2006.01) C07K 14/145 (2006.01) C12N 1/00 (2006.01) C12N 15/00 (2006.01) C12N 15/47 (2006.01)
Patent
CA 2431938
Disclosed herein is a novel vaccine formulation for prophylatic or therapeutic immunization of vertebrates against infections caused by vertebrate viruses. The said vaccine contains a minimum of two components, one of which is a deoxyribonucleotide (DNA) vaccine comprising of a DNA molecule that encodes a polypeptide of the virus and the other component consisting of inactivated form of the virus. This invention can also be used to develop low cost inactivated virus-based vaccines that contain much lower amount of the said virus than that present in similar vaccines known in the prior art. This invention also relates to a process of producing the said novel vaccine formulation and the use of the said formulation.
L'invention concerne une nouvelle formulation de vaccin en vue de l'immunisation préventive ou thérapeutique de vertébrés contre les infections causées par les virus des vertébrés. Ledit vaccin contient au minimum deux composants, dont un est un désoxyribonucléotide (ADN) constitué d'une molécule d'ADN qui code un polypeptide du virus et dont l'autre composant est constitué d'une forme inactivée du virus. L'invention peut également servir à mettre au point des vaccins à base d'un virus inactivé à faible coût contenant une quantité bien inférieure dudit vaccin que celle présente dans des vaccins semblables connus dans l'art antérieur. Cette invention concerne également un procédé d'obtention de la nouvelle formulation de vaccin et l'utilisation de ladite formulation.
Guddeti Sreenivasa Reddy
Pundi Narasimhan Rangarajan
Subhabrata Biswas
Villuppanoor Alwar Srinivasan
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Indian Immunologicals Limited
The Registrar Indian Institute Of Science
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