Thiazole derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 277/56 (2006.01) A61K 31/425 (2006.01) A61K 31/445 (2006.01) A61K 31/47 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) C07D 277/48 (2006.01) C07D 417/06 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2257322

Compounds of formula I Image as well as pharmaceutically usable salts and esters thereof, wherein R1, R2 and R3 have the significance given in claim 1, inhibit the binding of adhesive proteins to the surface of different types of cell and accordingly influence cell-cell and cell-matrix interactions. They can be used in the form of pharmaceutical preparations in the control or preventon of neoplasms, tumour metastasing, osteoporosis, Paget's disease, diabetic retinopathy, macular degeneration, restenosis following vascular intervention, psoriasis, arthritis, kidney failure as well as infections caused by viruses, bacteria or fungi.

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