Pseudotyped baculovirus and its use

Details Pseudotyped baculovirus and its use Pseudotyped baculovirus and its use

C - Chemistry, Metallurgy

12

N

C12N 15/866 (2006.01) A61K 48/00 (2006.01) C07K 14/01 (2006.01) C12N 7/01 (2006.01)

Patent

CA 2585886

A viral G protein-pseudotyped baculovirus, in which the G protein is truncated and comprises the ectodomain, transmembrane domain and cytoplasmic tail domain. Such a baculovirus can be used for transduction of cells and for gene therapy.

La présente invention a pour objet un baculovirus pseudotypé par une protéine G virale tronquée et comprenant l~ectodomaine, le domaine transmembranaire, et le domaine de queue cytoplasmique. Un tel baculovirus peut être employé pour la transduction de cellules dans le cadre d'une thérapie génique.

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