C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/31 (2006.01) A61K 39/00 (2006.01) C07K 14/37 (2006.01) C12N 1/14 (2006.01)
Patent
CA 2342948
Disclosed herein are attenuated forms of the B. dermatitidis fungus. The fungus remains replication competent but is unable to express the WI-1 protein. One can administer this fungus to a dog, human, or other mammal to vaccinate them against the wild type fungus. Preferably, the administration is by subcutaneous injection.
Brandhorst Theodore T.
Klein Bruce S.
Wuthrich Marcel
Borden Ladner Gervais Llp
Wisconsin Alumni Research Foundation
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