Purification of fluoromethyl 1,1,1,3,3,3-hexafluoroisopropyl...

C - Chemistry – Metallurgy – 07 – C

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C07C 41/09 (2006.01) C07C 41/42 (2006.01)

Patent

CA 2618345

Crude sevoflurane product comprising unacceptably high levels of HFIP can be purified by combining the crude sevoflurane product with sufficient water to produce a multiphase mixture, fractionally distilling the multiphase mixture, and removing substantially pure sevoflurane from the distilling multiphase mixture. It is emphasized that this abstract is provided to comply with the rules requiring an abstract which will allow a searcher or other reader quickly to ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the appended issued claims.

Des produits bruts de sevoflurane contenant des niveaux inacceptables de HFIP peuvent être purifiés de la manière suivante. A cette fin, on combine le produit brut de sevoflurane à un volume suffisant d'eau pour produire un mélange multiphase, on effectue une distillation par fractionnement dudit mélange pour en extraire du sevoflurane sensiblement pur.

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