Ligand that binds fas antigen

Details Ligand that binds fas antigen Ligand that binds fas antigen

C - Chemistry, Metallurgy

12

N

C12N 15/19 (2006.01) C07K 14/52 (2006.01) C07K 14/705 (2006.01) C07K 16/24 (2006.01) C07K 16/28 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2179909

Novel human and murine designated Fas ligand (Fas-L) bind to the cell surface protein known as Fas antigen. DNA sequences, expression vectors and transformed host cells useful in producing Fas-L polypeptides are provided, along with antibodies immunoreactive

L'invention a pour objet de nouvelles protéines humaines et murines appelées ligand de Fas (Fas-L). Ces protéines se fixent à la protéine de surface cellulaire connue sous le nom d'antigène Fas. L'invention a également pour objet les séquences d'ADN, les vecteurs d'expression et les cellules-hôtes transformées utiles dans la production de polypeptides de Fas-L, ainsi que les anticorps présentant une immunoréaction avec le Fas-L.

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