Cyclopentane heptan(ene)oic acid, 2-thiocarbamoyloxy and...

C - Chemistry – Metallurgy – 07 – C

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C07C 271/10 (2006.01) A61K 31/5575 (2006.01) A61P 27/06 (2006.01) C07C 271/26 (2006.01)

Patent

CA 2537794

The invention relates to the use of cyclopentane heptan(ene)oic acid, 2- thiocarbamoyloxy and carbamoyloxy as therapeutic agents e.g. as ocular hypotensives. The compounds used in accordance with the invention are represented by the following formula I (I) wherein a wavy segments indicate either the alpha (.alpha.) or beta (.beta.) configuration; the dashed bond represents a double bond or a single bond; U, Y, X, Rl , Ar, n, x and y are as defined in the specification.

L'invention concerne l'utilisation de l'acide cyclopentane heptan(en)oïque, de 2-thiocarbamoyloxy et de carbamoyloxy comme agents thérapeutiques, par exemple, comme hypotenseurs oculaires. Les composés utilisés selon l'invention sont représentés par la formule (I), dans laquelle: les liaisons ondulées signalent soit la configuration alpha (a) soit la configuration bêta (.szlig.); la liaison pointillée représente une double liaison ou une simple liaison. U, Y, X, R?1¿, Ar, n, x et y sont tels que définis dans la spécification.

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