Protease inhibitor conjugates and antibodies useful in...

C - Chemistry – Metallurgy – 12 – N

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C12N 5/18 (2006.01) C07D 401/14 (2006.01) C07D 417/12 (2006.01) C07D 495/04 (2006.01) C07K 16/38 (2006.01) C07K 16/44 (2006.01)

Patent

CA 2482232

Activated haptens useful for generating immunogens to HIV protease inhibitors, immunogens useful for producing antibodies to HIV protease inhibitors, and antibodies and labeled conjugates useful in immunoassays for HIV protease inhibitors. The novel haptens feature an activated functionality at the central, non-terminal hydroxyl group common to all HIV protease inhibitors, e.g., saquinavir, nelfinavir, indinavir, amprenavir, ritonavir, lopinavir, and atazanavir.

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