Use of dipyridamole in combination with antithrombotics for...

A - Human Necessities – 61 – K

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A61K 31/505 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2587026

The invention relates to a method of treating and preventing thromboembolic disorders, comprising administering dipyridamole in combination with an antithrombotic selected from direct thrombin inhibitors, factor Xa inhibitors and combined thrombin/factor Xa inhibitors to a patient, pharmaceutical compositions suitable for this method of treatment as well as the use of dipyridamole for the manufacture of these pharmaceutical compositions.

L'invention se rapporte à un procédé pour traiter et prévenir des troubles thromboemboliques, consistant à administrer, à un patient, du dipyridamole en association avec un antithrombotique sélectionné parmi des inhibiteurs directes de la thrombine, des inhibiteurs du facteur Xa, et une combinaison d'inhibiteurs directes de la thrombine et d'inhibiteurs du facteur Xa. Cette invention concerne en outre des compositions pharmaceutiques qui sont conçues pour ce procédé de traitement, et l'utilisation de dipyridamole pour produire lesdites compositions pharmaceutiques.

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