Monoclonal antibodies specific for human thymidylate synthase

Details Monoclonal antibodies specific for human thymidylate synthase Monoclonal antibodies specific for human thymidylate synthase

C - Chemistry, Metallurgy

12

P

C12P 21/08 (2006.01) C07K 16/30 (2006.01) C07K 16/40 (2006.01) C12N 5/18 (2006.01) G01N 33/573 (2006.01) G01N 33/574 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2109086

2109086 9219650 PCTABS00017 The present invention relates to monoclonal antibodies that are specific for the protein thymidylate synthase, and hybridomas producing these monoclonal antibodies. The invention further relates to methods of detection and diagnostic kits to test for the presence of thymidylate synthase. The invention also relates to the use of the monoclonal antibodies in determining the presence of colon carcinoma cells.

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