Compounds useful for the preparation of medicaments with...

Details Compounds useful for the preparation of medicaments with... Compounds useful for the preparation of medicaments with...

C - Chemistry, Metallurgy

07

C

C07C 69/734 (2006.01) A61K 31/165 (2006.01) A61K 31/198 (2006.01) A61K 31/216 (2006.01) A61K 31/223 (2006.01) A61P 1/00 (2006.01) C07C 59/90 (2006.01) C07C 229/36 (2006.01) C07C 233/47 (2006.01) C07C 259/06 (2006.01)

Patent

CA 2411162

Formula (I) compounds are described, where R1 and R2, which may be the same or different, are halogen, hydroxy, alkoxy, cycloalkoxy; X is (CH2)n-, -CO-(CH2)n- , where n is 1 or 2, or X is -CH=; R3 is -OH, -NHOH, alkoxy; Y is H, - (CH2)nCOR4, -COR4, -NHR5, where R4 is -OH, -NHOH, alkoxy, R5 is H, alkanoyl optionally substituted by halogens; n is an integer between 1 and 4; as well as processes for their preparation and their use as medicaments; particularly as selective phosphodiesterase IV inhibitors.

Composés représentés par la formule (I), dans laquelle les groupes sont définis dans les revendications, ainsi que procédés servant à préparer ces composés et leur utilisation en tant que médicaments, en particulier, en tant qu'inhibiteurs sélectifs de la phosphodiestérase IV.

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