Pyridinecarboxylic acid amide derivatives and pharmaceutical...

C - Chemistry – Metallurgy – 07 – D

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C07D 401/04 (2006.01) A61K 31/44 (2006.01) A61K 31/55 (2006.01) C07D 213/82 (2006.01)

Patent

CA 2049440

Compounds are disclosed of the formula (see formula I) wherein R1 is hydrogen, C1-C3 alkyl or diphenylmethyl; Y is -NH(CH2)n-R2; R2 is OH or -ONO2; m is 2 or 3; and n is 9 to 13 or physiologically acceptable acid addition salts thereof. The compounds of formula (I) are of a blood flow- increasing and hypotensive actions and can be used for the therapy or prevention of diseases in the cardiovascular system. 30

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