Tetrahydronaphthyridine derivative

Details Tetrahydronaphthyridine derivative Tetrahydronaphthyridine derivative

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/4985 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2624625

The invention relates to 6-[2-(1-Isopropyl-piperidin-4-yloxy)-7,8-dihydro-5H- [1 ,6]naphthyridin-6-yl]- nicotinamide of Formula (I) and to processes for the preparation of, compositions containing and the uses of, the compound. The compound is an H3 ligand and is useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.

La présente invention concerne le 6-[2-(1-isopropylpipéridin-4-yloxy)-7,8-dihydro-5H-[1,6]naphtyridin-6-yl]-nicotinamide et les procédés de synthèse dudit composé, les préparations contenant ledit composé et les applications dudit composé. Le composé est un ligand H3 et peut être employé dans le traitement de nombreuses maladies, troubles et états pathologiques, en particulier des maladies, troubles et états pathologiques inflammatoires, allergiques et respiratoires.

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