Monoclonal antibody sc104 and derivative thereof...

Details Monoclonal antibody sc104 and derivative thereof... Monoclonal antibody sc104 and derivative thereof...

C - Chemistry, Metallurgy

07

K

C07K 16/30 (2006.01) A61K 39/395 (2006.01) C07K 16/44 (2006.01)

Patent

CA 2563516

The present invention provides an isolated specific binding member capable of binding a sialyltetraosly carbohydrate and directly inducing cell death without the need for immune effector cells. Such a binding member may be an antibody or a part thereof. Also provided are the use of such binding members in medicine and nucleic acids encoding such binding members.

La présente invention concerne un élément de liaison spécifique isolé capable de fixer un glucide sialyltétraosyle et d'induire directement la mort cellulaire sans nécessiter de cellules effectrices immunes. Un tel élément de liaison peut être un anticorps ou une partie de celui-ci. L'invention concerne également l'utilisation de ces éléments de liaison en médecine ainsi que des acides nucléiques codant lesdits éléments de liaison.

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