Target recognizing binding agents

Details Target recognizing binding agents Target recognizing binding agents

C - Chemistry, Metallurgy

12

N

C12N 15/11 (2006.01) C07K 1/00 (2006.01) C07K 14/00 (2006.01) C07K 16/00 (2006.01) C07K 17/00 (2006.01) C12N 15/09 (2006.01) C12N 15/63 (2006.01) C40B 40/10 (2006.01) C40B 50/00 (2006.01) C40B 50/02 (2006.01) C40B 50/06 (2006.01) G06F 19/00 (2006.01)

Patent

CA 2510433

The invention is directed to binding agents having binding loops and a stable beta barrel conformation. The binding loops of these agents can easily be altered so that the binding agent can bind any selected target molecule. A variety of methods for generating binding agents with different binding loops are also provided.

L'invention concerne des agents de fixation présentant des boucles de fixation ainsi qu'une conformation en cylindre bêta stable. Les boucles de fixation de ces agents peuvent être modifiées facilement de manière que l'agent de fixation peut fixer n'importe quelle molécule cible. L'invention concerne également une variété de procédés permettant de générer des agents de fixation ayant différentes boucles de fixation.

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