A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/00 (2006.01)
Patent
CA 2625406
The present invention discloses and claims virus like particles (VLPs) that express and/or contains seasonal influenza virus proteins, avian influenza virus proteins and/or influenza virus proteins from viruses with pandemic potential. The invention includes vector constructs comprising said proteins, cells comprising said constructs, formulations and vaccines comprising VLPs of the inventions. The invention also includes methods of making and administrating VLPs to vertebrates, including methods of inducing substantial immunity to either seasonal and avian influenza, or at least one symptom thereof.
La présente invention concerne et revendique des particules semblables à des virus (VLP) qui expriment et/ou contiennent des protéines saisonnières du virus de la grippe, des protéines du virus de la grippe aviaire et/ou des protéines du virus de la grippe provenant de virus à potentiel pandémique. L'invention inclut des constructions de vecteurs comprenant lesdites protéines, des cellules qui comprennent lesdites constructions, des formules et des vaccins qui comprennent lesdits VLP de l~invention. L'invention comprend aussi des méthodes pour fabriquer et administrer des VLP aux vertébrés, y compris des méthodes pour induire une immunité substantielle contre une grippe saisonnière et/ou aviaire.
Bright Rick
Mahmood Kutub
Pushko Peter
Smith Gale
Zhang Jinyou
Deeth Williams Wall Llp
Novavax Inc.
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