Nucleotide and deduced amino acid sequences of tumor gene int6

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/12 (2006.01) A61K 38/17 (2006.01) A61K 39/00 (2006.01) A61K 48/00 (2006.01) C07H 21/00 (2006.01) C07K 14/82 (2006.01) C07K 16/32 (2006.01) C12Q 1/68 (2006.01) G01N 33/574 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2212573

The present invention discloses the isolation of the human and murine wild- type Int6 gene and the cDNAs corresponding to these genes. The invention further describes the use of reagents derived from the nucleic acid and amino acid sequences of the Int6 gene in diagnostic methods, immunotherapy, gene therapy and as vaccines.

Cette invention porte sur l'isolation d'un gène de type sauvage présent chez l'homme et la souris, le gène Int6, et les ADN complémentaires correspondants. Elle porte, en outre, sur l'utilisation de réactifs dérivés des séquences d'acide nucléique et d'acides aminés de ce gène Int6 à des techniques diagnostiques, à l'immunothérapie, à la thérapie génique et sur leur emploi comme vaccins.

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