A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/16 (2006.01) A61K 9/72 (2006.01) A61K 31/573 (2006.01) A61K 31/58 (2006.01) A61K 47/26 (2006.01) A61M 15/00 (2006.01)
Patent
CA 2481868
The invention relates to a method of producing an agglomerate of drug and solid binder. The process involves producing individual agglomerate particles and then converting the convertible amorphous content of same, following agglomeration, by the application of, for example, moisture. Agglomerates capable of conversion as well as the finished agglomerates and oral and nasal dosing systems including same are also contemplated. The process produces agglomerates which are rugged but which will produce an acceptable fine particle fraction during dosing.
Méthode de production d'un agglomérat formé d'un médicament et d'un liant solide. La méthode comprend la production de particules d'agglomérat individuelles et la conversion de la partie convertible amorphe de ces particules, après agglomération, notamment par application d'humidité. L'invention porte également sur des agglomérats pouvant être convertis ainsi que sur des agglomérats finis et des systèmes de dosage oral et nasal de ces agglomérats. La méthode produit des agglomérats grossiers, mais qui permettent d'obtenir une fraction particulaire d'une finesse acceptable lors du dosage.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Schering Corporation
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