Pteridinones used as plk (polo like kinase) inhibitors

Details Pteridinones used as plk (polo like kinase) inhibitors Pteridinones used as plk (polo like kinase) inhibitors

C - Chemistry, Metallurgy

07

D

C07D 475/00 (2006.01) A61K 31/505 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2575804

The invention relates to compounds of general formula (1), wherein L, Q1, Q2, X, Y, Ra, Rb, Rc, R1, R2, R3, and R4 are defined as indicated in claim 1. Said compounds are suitable for the treatment of diseases characterized by excessive or anomalous cell proliferation. Also disclosed is the use of said compounds for producing a medicament having said properties.

L'invention concerne des composés de formule générale (I), dans laquelle L, Q1, Q2, X, Y, Ra, Rb, Rc, R1, R2, R3 et R4 sont tels que définis dans la première revendication. Lesdits composés servent à traiter des maladies qui sont caractérisées par une prolifération cellulaire excessive ou anormale. Cette invention se rapporte en outre à l'utilisation de ces composés pour produire un médicament servant à traiter et/ou prévenir lesdites maladies.

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