A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/337 (2006.01) A61K 9/08 (2006.01) A61K 9/10 (2006.01) A61K 31/422 (2006.01) A61K 38/21 (2006.01) A61K 39/395 (2006.01) A61K 45/00 (2006.01) A61P 35/00 (2006.01) C07D 413/12 (2006.01) C07D 305/14 (2006.01)
Patent
CA 2365776
This invention relates to a method for treating abnormal cell proliferation in the brain by administering a compound of formula (I) or a pharmaceutically acceptable salt or hydrate thereof: in which R represents a hydrogen atom or an acetyl, alkoxyacetyl or alkyl radical, R1 represents a benzoyl radical or a radical R2-O-CO- wherein R2 represents an alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, bicycloalkyl, phenyl or heterocyclylic radical, and Ar represents an aryl radical.
La présente invention concerne une méthode de traitement de la prolifération de cellules anormales dans le cerveau, la méthode consistant à administrer un composé représenté par la formule (I) ou un sel ou hydrate de ce composé acceptable du point de vue pharmaceutique. Dans la formule (I) selon l'invention, R représente un atome d'hydrogène ou un radical acétyle, alcoxyacétyle ou alkyle; R¿1? représente un radical benzoyle ou un radical R¿2?-O-CO-, R¿2? représentant un radical alkyle, alcényle, alcynyle, cycloalkyle, cycloalcényle, bicycloalkyle, phényle ou hétérocyclique et Ar représente un radical aryle.
Besenval-Milleron Michele
Bissery Marie-Christine
Renard Alain
Aventis Pharma S.a.
Robic
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