Integrase-derived hiv-inhibiting agents

Details Integrase-derived hiv-inhibiting agents Integrase-derived hiv-inhibiting agents

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) A61K 31/7088 (2006.01) A61K 38/45 (2006.01) A61K 39/21 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) A61P 31/18 (2006.01) C07H 21/00 (2006.01) C07K 16/40 (2006.01) C07K 19/00 (2006.01) C12N 7/04 (2006.01) C12N 9/10 (2006.01) C12Q 1/02 (2006.01) C12Q 1/48 (2006.01) G01N 33/569 (2006.01) C07K 14/16 (2006.01) C07K 16/10 (2006.01) C12N 15/49 (2006.01)

Patent

CA 2568981

The present invention relates to agents based on integrase of HIV-1, for inhibiting the proliferation of HIV-1. The agents are derived from the C-terminal domain of HIV-1 integrase, comprising at least one of the regions identified as being important for interaction between integrase and imp7 or im.beta., and/or for nuclear localization of the HIV PIC, replication of HIV, or infection of HIV.

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