High throughput assay systems and methods for identifying...

Details High throughput assay systems and methods for identifying... High throughput assay systems and methods for identifying...

A - Human Necessities

61

K

A61K 31/495 (2006.01) C12Q 1/02 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2534438

Disclosed are high throughput assay systems and methods for identifying agents that alter the level of surface expression of integral membrane proteins, such as cardiac ion channels, in mammalian cells. Also disclosed are therapeutic methods of using agents identified using such methods.

L'invention concerne des systèmes et des procédés de dosage pour identifier les agents qui modifient le degré d'expression en surface des protéines de membrane intégrales qui modifient le degré d'expression en surface de protéines de membrane intégrales tels que les canaux ioniques cardiaques dans les cellules mammaliennes. L'invention concerne aussi des procédés thérapeutiques pour utiliser ces procédés au moyen des procédés décrits dans l'invention.

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