Use of a novel eimeria gene and corresponding protein

Details Use of a novel eimeria gene and corresponding protein Use of a novel eimeria gene and corresponding protein

C - Chemistry, Metallurgy

07

K

C07K 14/44 (2006.01) A61K 39/012 (2006.01) A61K 39/395 (2006.01)

Patent

CA 2531161

The invention relates to a novel oocyst sporocyst protein (Et0s22) belonging to the parasite of the species Eimeria tenella and to the polynucleotide encoding this protein, to vectors which contain this polynucleotide, to cells which are transformed with these vectors, to antibodies which are directed against the protein, to vaccines which comprise the polynucleotide, the protein, or fragments thereof, the abovementioned vectors or antibodies directed against the protein, and to the use of polynucleotide or of polypeptide for finding active compounds for treating an infection with Eimeria and active compounds which are suitable for the therapy of an infection with Eimeria.

L'invention concerne une nouvelle protéine oocyste sporocyste (EtOS22) appartenant au parasite de l'espèce Eimeria tenella et le polynucléotide codant cette protéine ; des vecteurs qui contiennent ce polynucléotide ; des cellules qui sont transformées au moyen de ces vecteurs ; des anticorps qui sont dirigés contre cette protéine ; des vaccins qui comprennent le polynucléotide, la protéine, ou des fragments associés, lesdits vecteurs ou anticorps dirigés contre la protéine ; et l'utilisation d'un polynucléotide ou polypeptide afin de trouver des composés actifs permettant de traiter un infection par Eimeria et des composés actifs aptes à être utilisés pour le traitement d'une infection par Eimeria.

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