Diagnostic assay for endometriosis

Details Diagnostic assay for endometriosis Diagnostic assay for endometriosis

G - Physics

01

N

G01N 33/564 (2006.01) G01N 33/543 (2006.01) G01N 33/58 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2406496

The present invention provides a method for detecting endometriosis in a patient and is an improvement over invasive and expensive surgical procedures. The method employs immunoassays which detect autoantibodies in a serum sample which react with Thomsen-Friedenreich antigen (Tf). Increased levels of autoantibodies in a serum sample from the patient which bind to Tf-like antigen is indicative of endometriosis in the patient.

L'invention concerne un procédé de détection de l'endométriose, chez une patiente, et elle constitue une amélioration par rapport aux procédures chirurgicales vulnérantes et coûteuses. Dans ce procédé, on utilise des immunodosages, lesquels détectent -dans un échantillon de sérum- des anticorps qui réagissent avec l'antigène de Thomsen-Friedenreich (Tf). Des taux accrus de ces anticorps présents dans un échantillon de sérum prélevé sur ladite patiente, et se liant à l'antigène de type Tf, indiquent une condition d'endométriose chez cette patiente.

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