Pyrrolopyrazine kinase inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 487/04 (2006.01) A61K 31/5025 (2006.01) A61P 29/00 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2716223

The present invention relates to the use of novel pyrrolopyrazine derivatives of Formula (I), wherein the variables Q1 and R are defined as described herein, which inhibit JAK and SYK and are useful for the treatment of auto-immune and in-flammatory diseases.

L'invention concerne l'utilisation de nouveaux dérivés de pyrrolopyrazine de Formule (I), dont les variables Q1 et R sont tels que définies dans le descriptif; ils inhibent JAK et SYK et s'utilisent pour le traitement de maladies auto-immunitaires et inflammatoires.

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