Method of using metaloporphyrins for treatment of...

A - Human Necessities – 61 – K

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A61K 51/00 (2006.01) A61K 31/40 (2006.01) A61P 9/10 (2006.01)

Patent

CA 2433114

A method for diagnosis and treatment of arteriosclerotic lesions is provided wherein the method is characterized by introducing a chemical compound to the patient, the compound being a complex of a photosensitive portion, and a radioactive portion. Cells which exhibit an affinity for the porphyrin element indicate sites of plaque buildup. The radioactive portion within the compound allows tomographic scanning as well as simultaneous radiation treatment. The complexed compound can be introduced to the patient a desired number of times to provide the necessary radiation treatment and ongoing monitoring of plaque removal. Further observation or treatment may be conducted through a fluorescence guided endoscopic procedure.

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