C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 215/68 (2006.01) A61K 31/421 (2006.01) A61P 3/06 (2006.01) C07D 213/38 (2006.01) C07D 263/34 (2006.01) C07D 277/22 (2006.01) C07D 333/58 (2006.01)
Patent
CA 2571356
The invention is concerned with novel hexafluoroisopropanol derivatives of formula (I), wherein R1 to R6, m and n are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds bind to LXR alpha and LXR beta and can be used as medicaments.
L'invention concerne de nouveaux dérivés d'hexafluoroisopropanol représentés par la formule générale (I), dans laquelle R1 à R6, m et n désignent des éléments définis dans la description et les revendications de la présente demande. L'invention concerne également des sels de qualité physiologique et des esters de ces dérivés. Ces composés se fixent aux LXR alpha et aux LXR bêta et peuvent être utilisés comme médicaments.
Blake Wright Matthew
Dehmlow Henrietta
Kuhn Bernd
Masciadri Raffaello
Panday Narendra
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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