A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/00 (2006.01) A61K 33/00 (2006.01)
Patent
CA 2616986
A physiologically acceptable perfluorocarbon emulsion composition that includes perfluorodecalin and an oxygen-carrying fluorinated surfactant forming a stable emulsion in a continuous aqueous phase. The oxygen-carrying fluorinated surfactant may be fractionated to increase its physiological compatibility, and may further include a fatty acid radical perfluorinated to increase its oxygen-carrying capacity. The perfluorocarbon emulsion composition of the present invention thus exhibits improved stability and efficiency, broadening its application and effectiveness as an artificial oxygen carrier.
L'invention concerne une composition d'émulsion de perfluorocarbone acceptable sur le plan physiologique comprenant de la perfluorodécaline et un tensioactif fluoré transporteur d'oxygène formant une émulsion stable dans une phase aqueuse continue. Le tensioactif fluoré transporteur d'oxygène peut être fractionné de manière à accroître la compatibilité physiologique de celui-ci et peut également comprendre un radical d'acide gras perfluoré aux fins d'augmentation de la capacité de transporter l'oxygène. La composition d'émulsion de perfluorocarbone selon l'invention présente, par conséquent, une stabilité et un rendement améliorés, élargissant ainsi l'application et l'efficacité de celle-ci comme transporteur d'oxygène artificiel.
Drees Thomas C.
Drees Thomas C.
Osler Hoskin & Harcourt Llp
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