Pharmaceutical compositions and methods comprising...

A - Human Necessities – 61 – K

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A61K 31/59 (2006.01) A61K 38/29 (2006.01) A61P 3/02 (2006.01) A61P 3/04 (2006.01) A61P 19/00 (2006.01) A61P 19/10 (2006.01) A61P 21/00 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2539357

The present invention relates to pharmaceutical compositions and methods of treatment comprising administering to a patient in need thereof a combination of a 2-alkylidene-19-nor-vitamin D derivative and parathyroid hormone or an active fragment or variant thereof. Particularly, the present invention relates to pharmaceutical compositions and methods of treatment comprising administering to a patient in, need thereof 2-methylene-19-nor-20(S)- 1.alpha.,25-dihydroxyvitamin D3 and parathyroid hormone or an active fragment or variant thereof.

L'invention concerne des compositions pharmaceutiques et des méthodes de traitement consistant à administrer à un patient nécessitant un tel traitement une association d'un dérivé de la 2-alkylidène-19-nor-vitamine D et de l'hormone parathyroïdienne ou bien d'un fragment actif ou d'une variante de celle-ci. Plus particulièrement, la présente invention concerne des compositions pharmaceutiques et des méthodes de traitement consistant à administrer à un patient nécessitant un tel traitement de la 2-méthylène-19-nor-20(S)-1.alpha.,25-dihydroxyvitamine D¿3? et de l'hormone parathyroïdienne ou bien un fragment actif ou une variante de celle-ci.

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