C - Chemistry – Metallurgy – 08 – F
Patent
C - Chemistry, Metallurgy
08
F
C08F 257/02 (2006.01) G01N 31/16 (2006.01) G01N 33/50 (2006.01)
Patent
CA 2610973
The present invention relates to processes for preparing carboxylated latex particles based on the copolymerization of a monoalkenylaromatic monomer (A) and an aliphatic unsaturated carboxylic acid (B), where the copolymerization takes place at a pH in the range from pH > 1.5 to pH < 4.5. The pH is preferably monitored during the copolymerization process and regulated by suitable compensatory titration. The invention likewise relates to the carboxylated latex particles obtainable by one of the processes according to the invention, and to the use of these particles in an immunological test method.
La présente invention concerne des procédés pour préparer des particules de latex carboxylé basé sur la copolymérisation d'un monomère monoalcénylaromatique (A) et d'un acide carboxylique aliphatique insaturé (B), la copolymérisation ayant lieu à un pH dans la gamme de pH supérieur à 1,5 et inférieur 4,5. Le pH est de préférence surveillé au cours du procédé de copolymérisation et régulé par titrage compensatoire approprié. L'invention concerne également les particules de latex carboxylé pouvant être obtenues par l~un des procédé selon l'invention, et l'utilisation de ces particules dans une méthode d~essai immunologique.
Frackmann Gernot
Geiger Albert
Moritz Hans-Ulrich
Sluka Peter
Borden Ladner Gervais Llp
F. Hoffmann-La Roche Ag
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