Peroral administration form for peptidic medicaments, in...

A - Human Necessities – 61 – K

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A61K 38/28 (2006.01) A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 9/24 (2006.01) A61K 9/50 (2006.01) A61K 9/51 (2006.01) A61K 47/42 (2006.01)

Patent

CA 2125284

A peroral administration form for peptidic medicaments contains the peptidic medicament, in particular insulin, distributed in a gelatine or gelatine derivate matrix, besides usual pharmaceutical excipients and additives. By selecting an appropriate gelatine, the medicament is released in the small or large intestine, so that it is no longer enzymatically decomposed by peptidases.

Une forme d'administration perorale de médicaments peptidiques contient un médicament peptidique, notamment l'insuline, répartie dans une matrice en gélatine ou en un dérivé de gélatine, en plus des excipients et des additifs pharmaceutiques usuels. La sélection d'une gélatine appropriée permet de libérer le médicament dans l'intestin grêle ou dans le gros intestin, de sorte qu'il ne soit plus enzymatiquement décomposé par les peptidases.

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