A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 35/74 (2006.01) A61P 1/02 (2006.01) A61P 31/04 (2006.01)
Patent
CA 2731500
The present invention relates to the preparation and use of a glycolipid fraction from Oscillatoria Planktothrix sp , for the treatment and/or prevention of bacterial gum diseases primarily caused by Actinobacillum actinomycetemconcomitans, Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola and even more preferably by Porphyromonas gingivalis Said gum diseases, in particular gingivitis and periodontitis (pyorrhea), are primarily caused by a pro-inflammatory response to components of P gingivalis, leading to destruction of periodontal tissue, and are often accompanied by osteoclastogenesis (in-creased number of osteoclasts responsible for destruction of bone tissue), and by chronic infection
La présente invention concerne la préparation et l'utilisation d'une fraction de glycolipide provenant d'Oscillatoria Planktothrix sp., destinée au traitement et/ou à la prévention de maladies gingivales bactériennes provoquées principalement par Actinobacillum actinomycetemconcomitans, Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola, et de préférence encore par Porphyromonas gingivalis. Lesdites maladies, en particulier la gingivite et la parodontite (pyorrhée), sont provoquées principalement par une réponse pro-inflammatoire aux composants de P. gingivalis, menant à la destruction du tissu parodontal, et s'accompagnent souvent d'ostéoclastogenèse (augmentation du nombre des ostéoclastes responsables de la destruction du tissu osseux), et d'infection chronique.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Bluegreen Biotech S.r.l.
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