A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/22 (2006.01) A61K 9/08 (2006.01) A61K 31/19 (2006.01) A61K 31/192 (2006.01) A61K 31/221 (2006.01) A61K 31/355 (2006.01)
Patent
CA 2245509
Certain incidents in mammals trigger the generation of free-radicals which are associated with cell death. Animals experiencing such medical incidents are dosed with pyruvate salts or esters in an amount of 5 to 20 weight percent of the total carbohydrate intake. The dosage of pyruvate may be provided to the animal before the medical incident, during the medical incident, and after the medical incident. In addition to the known property in pyruvate for scavenging free-radicals, this disclosure points out the unexpected effectiveness of pyruvate as an inhibitor of free-radical generation.
Certains incidents chez les mammifères peuvent déclencher la génération de radicaux libres associés à la mort de la cellule. On administre aux animaux chez lesquels se produisent de tels incidents, des sels ou des esters de pyruvate dans une quantité représentant de 5 à 20 % en poids de la quantité totale d'hydrate de carbone absorbé. Ce dosage de pyruvate peut être administré à l'animal avant, pendant, ou après l'incident médical. Outre les propriétés connues du pyruvate en ce qui concerne le piégeage des radicaux libres, cette invention permet également de démontrer l'efficacité surprenante du pyruvate en tant qu'inhibiteur de génération de radicaux libres.
Borden Ladner Gervais Llp
Stanko Ronald T.
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