Inhibition of hairless protein mrna

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01) A61K 48/00 (2006.01) C07H 21/04 (2006.01)

Patent

CA 2557532

Methods for inhibition of hairless protein mRNA using RNA interference is described, in particular methods for hair removal. Also described are nucleic acid constructs for RNAi-mediated inhibition of hairless protein mRNA and compositions including such constructs.

L'invention concerne des méthodes d'inhibition d'un ARNm associé à une protéine du gène hairless (sans poil) par interférence ARN, en particulier des méthodes d'élimination des poils. L'invention concerne également des constructions d'acides nucléiques utilisées dans l'inhibition médiée par un ARNi de l'ARNm associé à une protéine du gène hairless, et des compositions contenant lesdites constructions.

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