Treatment of certain cancers associated with weight gain

Details Treatment of certain cancers associated with weight gain Treatment of certain cancers associated with weight gain

A - Human Necessities

61

K

A61K 31/135 (2006.01) A61K 31/137 (2006.01)

Patent

CA 2367045

A compound of formula (I) or a pharmaceutically acceptable salt thereof in which R1 and R2 are independently H or methyl (for example <u>N</u>,<u>N</u>- dimethyl-1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutyl amine hydrochloride optionally in the form of its monohydrate) is used for treating cancers associated with obesity including colon cancer, breast cancer, endometrial cancer and gallbladder cancer.

L'invention concerne un composé représenté par la formule (I) ou un sel de ce composé acceptable du point de vue pharmaceutique, R¿1? et R¿2? représentant indépendamment H ou un méthyle (par exemple un hydrochlorure d'amine <u>N</u>,<u>N</u>-diméthyl-1-[1-(4-chlorophényl)cyclobutyl]-3-méthylbutyle éventuellement sous la forme de son monohydrate). Ce composé s'utilise dans le traitement de cancers associés à l'obésité, y compris le cancer du côlon, le cancer du sein, le cancer de l'endomètre et le cancer de la vésicule biliaire.

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