Orphan receptor tyrosine kinase as a target in breast cancer

Details Orphan receptor tyrosine kinase as a target in breast cancer Orphan receptor tyrosine kinase as a target in breast cancer

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) G01N 33/48 (2006.01) G01N 33/50 (2006.01) G06F 19/00 (2006.01)

Patent

CA 2563333

Methods and materials relating to the orphan receptor tyrosine kinase (ROR1) are described. ROR1 exhibits restricted tissue expression in normal adult tissue and is overexpressed in certain breast cancer subtypes. ROR1 provides a diagnostic and/or therapeutic target for breast cancers.

La présente invention a trait à des procédés et des substances concernant le récepteur à activité tyrosine kinase orphelin (ROR1). Le ROR1 présente une expression tissulaire restreinte dans un tissu adulte normal et est surexprimé dans certains sous-types de cancer du sein. Le ROR1 fournit une cible diagnostique et/ou thérapeutique pour les cancers du sein.

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