Quinoxaline derivatives useful in therapy

Details Quinoxaline derivatives useful in therapy Quinoxaline derivatives useful in therapy

C - Chemistry, Metallurgy

07

D

C07D 241/44 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2200742

Compounds of formula (I), wherein A represents N or CH; R1 and R2 independently represent C1-4 alkyl, halo or CF3; R3 represents C1-4 alkyl (optionally substituted), C3-7 cycloalkyl, CF3 or aryl; and R4 represents H, C3-7 cycloalkyl or C1-6 alkyl (optionally substituted); and their pharmaceutically acceptable derivatives; are useful in the treatment of, inter alia, neurodegenerative disorders.

Composés de la formule (I), ainsi que leurs dérivés acceptables sur le plan pharmacologique, dans laquelle A représente N ou CH; R<1> et R<2> représentent indépendamment alkyle C1-4, halo ou CF3; R<3> représente alkyle C1-4 (éventuellement substitué), cycloalkyle C3-7, CF3 ou aryle; et R<4> représente H, cycloalkyle C3-7 ou alkyle C1-6 (éventuellement substitué). Ces composés sont utiles dans le traitement, entre autres, des affections dégénératives neuronales.

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