Method and compositions for inhibiting adhesion formation

Details Method and compositions for inhibiting adhesion formation Method and compositions for inhibiting adhesion formation

A - Human Necessities

61

K

A61K 38/16 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) C07K 14/00 (2006.01) C07K 14/435 (2006.01) C07K 16/00 (2006.01) C07K 16/28 (2006.01)

Patent

CA 2384812

Compositions and methods for inhibiting or ameliorating post-operative/post- wounding adhesion formation in patients are disclosed. Such compositions and methods utilize an antagonist molecule that blocks or inhibits alpha V beta 3 integrin binding to an extra cellular matrix protein such as fibronectin.

L'invention concerne des compositions et des procédés pour inhiber ou améliorer la formation d'adhérences chez un patient à l'issue d'une intervention chirurgicale ou de cicatrisation. Ces compositions et procédés utilisent une molécule antagoniste qui bloque ou inhibe l'intégrine alpha V bêta 3 se liant à une protéine de matrice extracellulaire telle que la fibronectine.

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