Novel aryl n-alkylacridancarboxylate derivatives useful for...

Details Novel aryl n-alkylacridancarboxylate derivatives useful for... Novel aryl n-alkylacridancarboxylate derivatives useful for...

C - Chemistry, Metallurgy

07

D

C07D 219/04 (2006.01) C07D 219/02 (2006.01) C07D 219/06 (2006.01) C07D 401/02 (2006.01) C12Q 1/28 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/532 (2006.01) G01N 33/58 (2006.01)

Patent

CA 2184612

Acridans which are reactable with a peroxidase and peroxide. The acridans are characterized by having an aromatic leaving group ArO which is a di- or polyhalosubstituted phenoxy group. The compounds are useful in assays where one member of a binding pair is linked to the peroxidase and for detecting the peroxidase. The method can also be used to detect hydrogen peroxide.

On décrit des acridanes qui peuvent réagir avec une peroxydase et un peroxyde. Ils se caractérisent par un groupe aromatique partant, ArO, qui est un groupe phénoxy di- ou polyhalo-substitué. Ces composés s'utilisent pour des titrages où un élément d'une paire de liaison est lié à la peroxydase, et afin de détecter cette peroxydase. On peut aussi utiliser un tel procédé pour détecter le peroxyde d'hydrogène.

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