Recombinant infectious non-segmented negative strand rna virus

Details Recombinant infectious non-segmented negative strand rna virus Recombinant infectious non-segmented negative strand rna virus

C - Chemistry, Metallurgy

12

N

C12N 15/86 (2006.01) A61K 39/155 (2006.01) A61K 39/205 (2006.01) A61K 39/295 (2006.01) C07K 14/145 (2006.01) C07K 14/16 (2006.01) C07K 14/18 (2006.01) C12N 7/01 (2006.01) C12N 7/04 (2006.01) C12N 15/45 (2006.01) C12N 15/47 (2006.01) C12N 15/62 (2006.01)

Patent

CA 2154023

The present invention provides the generation of infectious replicating non- segmented negative-stranded RNA virus, entirely from cloned cDNA. This process offers the possibility to introduce mutations into the virus genome by means of recombinant DNA techniques.

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