C - Chemistry – Metallurgy – 07 – J
Patent
C - Chemistry, Metallurgy
07
J
C07J 17/00 (2006.01) A61K 31/705 (1995.01)
Patent
CA 2218724
This invention relates to ginsenoside Mc with formula (I), an intestinal flora metabolite of ginseng saponin and anticancer agent containing it as an active ingredient. In addition to a novel compound, the anticancer agent of this invention consists of one active ingredient selected from compound K, compound Y or 20(S)-protopanaxatriol, intestinal flora metabolites of ginseng saponin, together with one or more pharmaceutically acceptable carriers. Said agent is a novel type of potential anticancer agent since it has immunopotentiating actions including inhibitory actions on the vascularization of tumors and extravasation of cancer cells.
Ginsenoside Mc répondant à la formule (I), métabolite de la saponine du ginseng produit par la flore intestinale, et agent anticancéreux le renfermant à titre d'ingrédient actif. Outre un nouveau composé, l'agent anticancéreux est constitué d'un ingrédient actif choisi parmi le composé K, le composé Y ou le 20(S)-protopanaxatriol, et les métabolites de la saponine du ginseng produits par la flore intestinale, en association avec un ou plusieurs excipients pharmaceutiquement acceptables. Ledit agent est un nouveau type d'agent anticancéreux car il présente une activité immunostimulante et une activité d'inhibition de la vascularisation des tumeurs et de l'extravasation des cellules cancéreuses.
Hideo Hasegawa
Huh Jae Doo
Masamori Uchiyama
Satoshi Matsumiya
Sung Jong Hwan
Happy World Inc.
Il Hwa Co. Ltd.
R. William Wray & Associates
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