Method for isolating (r)-tofisopam

Details Method for isolating (r)-tofisopam Method for isolating (r)-tofisopam

C - Chemistry, Metallurgy

07

D

C07D 243/10 (2006.01)

Patent

CA 2633285

The present invention is directed to a process for the isolation of (R)- tofisopam with high enantiomeric purity and high overall yields from a mixture of tofEsopam enantiomers by means of a non- simulated moving bed chromatographic process.

Cette invention concerne un procédé d'isolement de (R)-tofisopam permettant d'obtenir une grande pureté énantiomérique et des rendements globaux élevés à partir d'un mélange d'énantiomères de tofisopam au moyen d'un procédé de chromatographie à lit mobile non simulé.

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