Process for the manufacture of etherified hydroxy-...

C - Chemistry – Metallurgy – 07 – D

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C07D 235/26 (2006.01) C07C 205/37 (2006.01) C07C 205/42 (2006.01) C07C 205/43 (2006.01) C07D 239/80 (2006.01) C07D 239/96 (2006.01) C07D 241/44 (2006.01) C07D 263/58 (2006.01) C07D 265/18 (2006.01) C07D 265/36 (2006.01) C07D 285/10 (2006.01) C07D 303/22 (2006.01) C07D 303/24 (2006.01) C07D 309/12 (2006.01)

Patent

CA 1083150

Abstract of the Disclosure Compounds if the formula (I) Image in which R1 denotes optionally substituted lower alkyl which is optionally branched at the linking carbon atom, R2 repres- ents hydrogen or lower alkanoyl and R3 is a group of the formula -R?-(R?)n-(Ia), in which R3 represents the radical of the formula -N(R4)- or -O- and R4 represents hydrogen or lower alkyl, R? denotes the radical of the formula -CH2- or, if R? represents -N(R4)-, denotes the radical of the formula -C(=O)- and n represents nought or 1, and a group of the formula Ia, in which n represents 1, can be linked to the carbonyl group of - 1 - the carbamoyl grouping either via the group R? or the group R?, or acid addition salts thereof, which can be used pharma- ceutically can be used as beta-receptor-blocking agents for the treatment of disorders in the cardiac rhythm and coronary heart diseases. These compounds also possess a cardio- stimulating action; some of them also display alpha-receptor- blocking properties. - 1a -

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