Method for quantitating an inflammatory response

G - Physics – 01 – N

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G01N 33/564 (2006.01) G01N 33/543 (2006.01) G01N 33/554 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2231882

A method for objectively quantitating the cellular infiltration in a tissue biopsy of a warm-blooded animal using a capture ELISA method. This method also allows one to quantitate the cellular infiltration of a tissue biopsy corresponding to an inflammatory response. As such this invention has both research and clinical applications in the analysis of an inflammatory response, and the effectiveness of immunosuppressants in addressing the inflammation.

L'invention concerne un procédé pour quantifier objectivement l'infiltration cellulaire dans une biopsie tissulaire d'un animal à sang chaud en utilisant une technique Elisa en sandwich. Cette technique permet également de quantifier une réaction inflammatoire, à partir de l'infiltration cellulaire d'une biopsie tissulaire. Cette invention peut être mise en oeuvre, en recherche ou en clinique, pour effectuer une analyse d'une réponse inflammatoire et une évaluation de l'efficacité d'immunosuppresseurs pour traiter les inflammations.

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